One of the main reasons that tobacco, nicotine, or smoking addictions are so powerful is because they stimulate an artificially high production of neurotransmitters and hormones that create an imbalance in the “reward system” of the brain. At Theta Wellness Center, our doctors and professionals can help you overcome your tobacco, nicotine, or smoking addiction in Sandy, Utah. Instead of just learning to resist the urge for a smoke or chew of tobacco, Mike Simpson, Diana Simpson, Dr. Stuart Porter, and Dr. Bonnie Warinski can help you overcome your desire to indulge. Call us today at 801-590-7461 for more information, and to begin your treatment sessions today.

According to NIDA, “Addiction changes brain circuitry, making it hard to “apply the brakes” to detrimental behaviors. In the non-addicted brain, control mechanisms constantly assess the value of stimuli and the appropriateness of the planned response. Inhibitory control is then applied as needed. In the addicted brain, this control circuit becomes impaired because of drug use and loses much of its inhibitory power over the circuits that drive responses to stimuli deemed salient.”

In other words, altered brain chemistry is the root of the problem. Any treatment that fails to normalize brain chemistry has little chance of success. In other words, instead of quitting smoking cold turkey or using “stop smoking aids,” it turns out that the best way to quit smoking is to correct brain chemistry.

Nicotine’s Effect on the Brain

Modern research shows that nicotine acts on the brain to produce a number of effects. Specifically, research examining its addictive nature has been found to show that nicotine activates the mesolimbic pathway (“reward system”) – the circuitry within the brain that regulates feelings of pleasure and euphoria.

Dopamine is one of the key neurotransmitters actively involved in the brain. Research shows that by increasing the levels of dopamine within the reward circuits in the brain, nicotine acts as a chemical with intense addictive qualities. In many studies, it has been shown to be more addictive than cocaine and heroin.

Withdrawal Symptoms

Like other physically addictive drugs, nicotine withdrawal causes down-regulation of the production of dopamine and other stimulatory neurotransmitters as the brain attempts to compensate for artificial stimulation. To compensate, the brain in turn increases the number of receptors. The net effect is an increase in reward pathway sensitivity, the opposite of other addictive drugs such as cocaine and heroin, which reduce reward pathway sensitivity. This brain alteration can persist for months. Often nicotine withdrawal causes months or years of depression.

Mood Altering Effects

Nicotine acts as both a stimulant and a relaxant. First causing a release of glucose and epinephrine (adrenaline), it causes stimulation. Users report feelings of relaxation, sharpness, calmness, and alertness.

When a cigarette is smoked, nicotine-rich blood passes from the lungs to the brain within seven seconds and immediately stimulates the release of many chemical messengers (neurotransmitters and hormones) which are responsible for most of nicotine’s effects. Nicotine also extends the duration of the effects of dopamine and increases sensitivity in brain reward systems.

Nicotine produces significant behavioral sensitization, a measure of addiction potential. This is similar in effect to amphetamine.


Most cigarettes (in the smoke inhaled) contain 1 to 3 milligrams of nicotine. Research suggests that, when smokers wish to achieve a stimulating effect, they take short quick puffs, which produce a low level of blood nicotine. This stimulates nerve transmission. When they wish to relax, they take deep puffs, which produce a high level of blood nicotine, which depresses the passage of nerve impulses, producing a mild sedative effect. At low doses, nicotine potently enhances the actions of norepinephrine and dopamine in the brain, causing a drug effect typical of those of psychostimulants. At higher doses, nicotine enhances the effect of serotonin and opiate activity, producing a calming, pain-killing effect. Nicotine is unique in comparison to most drugs, as its profile changes from stimulant to sedative/pain killer in increasing dosages and use.

Health Effects

Nicotine increases blood pressure and heart rate, and risk of atherosclerosis. It also has many other effects, including abolishment of the beneficial and protective effects of estrogen in the brain, which is involved in memory formation and retention.

A Hard Habit to Break

The stimulant effect is the main factor responsible for the dependence-forming properties of tobacco smoking. According to the American Heart Association, nicotine addiction has historically been one of the hardest addictions to break, while the pharmacological and behavioral characteristics that determine tobacco addiction are similar to those determining addiction to heroin and cocaine. The nicotine content of popular American-brand cigarettes has slowly increased over the years, and one study found that there was an average increase of 1.6% per year between the years of 1998 and 2005. This was found for all major market categories of cigarettes.

Quitting smoking cold turkey is not always the best way to quit smoking. Sometimes “stop smoking aids” can be helpful in weaning and ultimately quitting smoking. However, the process is much easier when combined with Theta Chamber℠ technology, which Theta Wellness Center offers patients.

Please contact our office to inquire about getting your consultation.